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Integrated genomics of susceptibility to alkylator-induced leukemia in mice
BACKGROUND: Therapy-related acute myeloid leukemia (t-AML) is a secondary, generally incurable, malignancy attributable to chemotherapy exposure. Although there is a genetic component to t-AML susceptibility in mice, the relevant loci and the mechanism(s) by which they contribute to t-AML are largel...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018144/ https://www.ncbi.nlm.nih.gov/pubmed/21080971 http://dx.doi.org/10.1186/1471-2164-11-638 |