Cargando…

A comprehensive map of the mTOR signaling network

The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation. mTOR signaling is frequently dysregulated in oncogenic cells, and thus an attractive target for anticancer therapy. Using CellDesigner, a modeling support software for graphical notation, we present her...

Descripción completa

Detalles Bibliográficos
Autores principales: Caron, Etienne, Ghosh, Samik, Matsuoka, Yukiko, Ashton-Beaucage, Dariel, Therrien, Marc, Lemieux, Sébastien, Perreault, Claude, Roux, Philippe P, Kitano, Hiroaki
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018167/
https://www.ncbi.nlm.nih.gov/pubmed/21179025
http://dx.doi.org/10.1038/msb.2010.108