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A tunable dual-promoter integrator for targeting of cancer cells

Precise discrimination between similar cellular states is essential for autonomous decision-making scenarios, such as in vivo targeting of diseased cells. Discrimination could be achieved by delivering an effector gene expressed under a highly active context-specific promoter. Yet, a single-promoter...

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Detalles Bibliográficos
Autores principales: Nissim, Lior, Bar-Ziv, Roy H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018173/
https://www.ncbi.nlm.nih.gov/pubmed/21179016
http://dx.doi.org/10.1038/msb.2010.99