An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions

Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by their binding to specific antigens. As an alternative approach, we propose to identify specific complementarity determining regions (CDR) of I...

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Detalles Bibliográficos
Autores principales: Dekker, Lennard J. M., Zeneyedpour, Lona, Brouwer, Eric, van Duijn, Martijn M., Sillevis Smitt, Peter A. E., Luider, Theo M.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018266/
https://www.ncbi.nlm.nih.gov/pubmed/21107826
http://dx.doi.org/10.1007/s00216-010-4361-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018266/
https://www.ncbi.nlm.nih.gov/pubmed/21107826
http://dx.doi.org/10.1007/s00216-010-4361-9

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