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An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions
Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by their binding to specific antigens. As an alternative approach, we propose to identify specific complementarity determining regions (CDR) of I...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018266/ https://www.ncbi.nlm.nih.gov/pubmed/21107826 http://dx.doi.org/10.1007/s00216-010-4361-9 |