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Organelle Membrane Proteomics Reveals Differential Influence of Mycobacterial Lipoglycans on Macrophage Phagosome Maturation and Autophagosome Accumulation

[Image: see text] The mycobacterial cell wall component lipoarabinomannan (LAM) has been described as one of the key virulence factors of Mycobacterium tuberculosis. Modification of the terminal arabinan residues of this lipoglycan with mannose caps in M. tuberculosis or with phosphoinositol caps in...

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Detalles Bibliográficos
Autores principales: Shui, Wenqing, Petzold, Christopher J., Redding, Alyssa, Liu, Jun, Pitcher, Austin, Sheu, Leslie, Hsieh, Tsung-yen, Keasling, Jay D., Bertozzi, Carolyn R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018347/
https://www.ncbi.nlm.nih.gov/pubmed/21105745
http://dx.doi.org/10.1021/pr100688h