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Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures

BACKGROUND: The rostral telencephalic dorsal midline is an organizing center critical for the formation of the future cortex and hippocampus. While the intersection of WNTs, BMPs, and FGFs establishes boundaries within this critical center, a direct role of Shh signaling in this region remains contr...

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Detalles Bibliográficos
Autores principales: Himmelstein, Diana S, Bi, Chunming, Clark, Brian S, Bai, Brian, Kohtz, Jhumku D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018372/
https://www.ncbi.nlm.nih.gov/pubmed/21114856
http://dx.doi.org/10.1186/1471-213X-10-118