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Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells

BACKGROUND: Zearalenone (ZEA) is a phytoestrogen from Fusarium species. The aims of the study was to identify mode of human leukemic cell death induced by ZEA and the mechanisms involved. METHODS: Cell cytotoxicity of ZEA on human leukemic HL-60, U937 and peripheral blood mononuclear cells (PBMCs) w...

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Detalles Bibliográficos
Autores principales: Banjerdpongchai, Ratana, Kongtawelert, Prachya, Khantamat, Orawan, Srisomsap, Chantragan, Chokchaichamnankit, Daranee, Subhasitanont, Pantipa, Svasti, Jisnuson
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018374/
https://www.ncbi.nlm.nih.gov/pubmed/21190589
http://dx.doi.org/10.1186/1756-8722-3-50