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In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine

BACKGROUND: Coccidioidomycosis or Valley fever is caused by a highly virulent fungal pathogen: Coccidioides posadasii or immitis. Vaccine development against Coccidioides is of contemporary interest because a large number of relapses and clinical failures are reported with antifungal agents. An effi...

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Detalles Bibliográficos
Autores principales: Vilekar, Prachi, Awasthi, Vibhudutta, Lagisetty, Pallavi, King, Catherine, Shankar, Nathan, Awasthi, Shanjana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018378/
https://www.ncbi.nlm.nih.gov/pubmed/21143974
http://dx.doi.org/10.1186/1471-2172-11-60