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Generation of Cell Lines to Complement Adenovirus Vectors using Recombination-Mediated Cassette Exchange
BACKGROUND: Adenovirus serotype 5 (Ad5) has many favourable characteristics for development as a gene therapy vector. However, the utility of current Ad5 vectors is limited by transient transgene expression, toxicity and immunogenicity. The most promising form of vector is the high capacity type, wh...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018391/ https://www.ncbi.nlm.nih.gov/pubmed/21182761 http://dx.doi.org/10.1186/1472-6750-10-92 |