3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"

BACKGROUND: In cancer cells the three-dimensional (3D) telomere organization of interphase nuclei into a telomeric disk is heavily distorted and aggregates are found. In Hodgkin's lymphoma quantitative FISH (3D Q-FISH) reveals a major impact of nuclear telomere dynamics during the transition fo...

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Detalles Bibliográficos
Autores principales: Knecht, Hans, Brüderlein, Silke, Wegener, Silke, Lichtensztejn, Daniel, Lichtensztejn, Zelda, Lemieux, Bruno, Möller, Peter, Mai, Sabine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018409/
https://www.ncbi.nlm.nih.gov/pubmed/21144060
http://dx.doi.org/10.1186/1471-2121-11-99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018409/
https://www.ncbi.nlm.nih.gov/pubmed/21144060
http://dx.doi.org/10.1186/1471-2121-11-99

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