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Monitoring the Long-Term Molecular Epidemiology of the Pneumococcus and Detection of Potential ‘Vaccine Escape’ Strains

BACKGROUND: While the pneumococcal protein conjugate vaccines reduce the incidence in invasive pneumococcal disease (IPD), serotype replacement remains a major concern. Thus, serotype-independent protection with vaccines targeting virulence genes, such as PspA, have been pursued. PspA is comprised o...

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Detalles Bibliográficos
Autores principales: Pandya, Gagan A., McEllistrem, M. Catherine, Venepally, Pratap, Holmes, Michael H., Jarrahi, Behnam, Sanka, Ravi, Liu, Jia, Karamycheva, Svetlana A., Bai, Yun, Fleischmann, Robert D., Peterson, Scott N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018475/
https://www.ncbi.nlm.nih.gov/pubmed/21264340
http://dx.doi.org/10.1371/journal.pone.0015950