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Combinations of Physiologic Estrogens with Xenoestrogens Alter ERK Phosphorylation Profiles in Rat Pituitary Cells

BACKGROUND: Estrogens are potent nongenomic phospho-activators of extracellular-signal–regulated kinases (ERKs). A major concern about the toxicity of xenoestrogens (XEs) is potential alteration of responses to physiologic estrogens when XEs are present simultaneously. OBJECTIVES: We examined estrog...

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Detalles Bibliográficos
Autores principales: Jeng, Yow-Jiun, Watson, Cheryl S.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018487/
https://www.ncbi.nlm.nih.gov/pubmed/20870566
http://dx.doi.org/10.1289/ehp.1002512