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PAC1 Deficiency in a Murine Model Induces Gastric Mucosa Hypertrophy and Higher Basal Gastric Acid Output

Pituitary adenylate cyclase-activating polypeptide (PACAP) has been shown to increase the histamine release from gastric enterochromaffin-like (ECL) cells and promote gastric acid secretion in rats. In contrast, in mice, PACAP has been demonstrated to induce a decrease of gastric acid secretion, an...

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Detalles Bibliográficos
Autores principales: Lu, Yuxin, Germano, Patrizia, Ohning, Gordon V., Vu, John P., Pisegna, Joseph R.
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018609/
https://www.ncbi.nlm.nih.gov/pubmed/20821075
http://dx.doi.org/10.1007/s12031-010-9440-z