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Induction of Granulysin and Perforin Cytolytic Mediator Expression in 10-Week-Old Infants Vaccinated with BCG at Birth

Background. While vaccination at birth with Mycobacterium bovis Bacilli Calmette-Guérin (BCG) protects against severe childhood tuberculosis, there is no consensus as to which components of the BCG-induced immune response mediate this protection. However, granulysin and perforin, found in the granul...

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Detalles Bibliográficos
Autores principales: Semple, Patricia L., Watkins, Marcia, Davids, Virginia, Krensky, Alan M., Hanekom, Willem A., Kaplan, Gilla, Ress, Stanley
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018618/
https://www.ncbi.nlm.nih.gov/pubmed/21234358
http://dx.doi.org/10.1155/2011/438463