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Correlation of Copper Interaction, Copper-Driven Aggregation, and Copper-Driven H(2)O(2) Formation with Aβ40 Conformation

The neurotoxicity of Aβ is associated with the formation of free radical by interacting with redox active metals such as Cu(2+). However, the relationship between ion-interaction, ion-driven free radical formation, and Aβ conformation remains to be further elucidated. In the present study, we invest...

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Detalles Bibliográficos
Autores principales: Yang, Chia-Anne, Chen, Yung-Han, Ke, Shyue-Chu, Chen, Yi-Ru, Huang, Hsien-Bin, Lin, Ta-Hsien, Chen, Yi-Cheng
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018625/
https://www.ncbi.nlm.nih.gov/pubmed/21234305
http://dx.doi.org/10.4061/2011/607861