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Correlation of Copper Interaction, Copper-Driven Aggregation, and Copper-Driven H(2)O(2) Formation with Aβ40 Conformation
The neurotoxicity of Aβ is associated with the formation of free radical by interacting with redox active metals such as Cu(2+). However, the relationship between ion-interaction, ion-driven free radical formation, and Aβ conformation remains to be further elucidated. In the present study, we invest...
Autores principales: | Yang, Chia-Anne, Chen, Yung-Han, Ke, Shyue-Chu, Chen, Yi-Ru, Huang, Hsien-Bin, Lin, Ta-Hsien, Chen, Yi-Cheng |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018625/ https://www.ncbi.nlm.nih.gov/pubmed/21234305 http://dx.doi.org/10.4061/2011/607861 |
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