Dynamics and Mechanism of Repair of UV-induced (6-4) Photoproduct by Photolyase

One of the detrimental effects of UV radiation on DNA is the formation of the (6-4) photoproduct (6-4PP) between two adjacent pyrimidines1. This lesion interferes with replication and transcription and may result in mutation and cell death2. In many organisms a flavoenzyme called photolyase uses blu...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Liu, Zheyun, Tan, Chuang, Guo, Xunmin, Wang, Lijuan, Sancar, Aziz, Zhong, Dongping
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018752/
https://www.ncbi.nlm.nih.gov/pubmed/20657578
http://dx.doi.org/10.1038/nature09192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018752/
https://www.ncbi.nlm.nih.gov/pubmed/20657578
http://dx.doi.org/10.1038/nature09192

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