Synthesis of a Versatile Building Block for the Preparation of 6-N-Derivatized α-Galactosyl Ceramides: Rapid Access to Biologically Active Glycolipids

[Image: see text] A concise route to the 6-azido-6-deoxy-α-galactosyl-phytosphingosine derivative 9 is reported. Orthogonal protection of the two amino groups allows elaboration of 9 into a range of 6-N-derivatized α-galactosyl ceramides by late-stage introduction of the acyl chain of the ceramide a...

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Detalles Bibliográficos
Autores principales: Jervis, Peter J., Cox, Liam R., Besra, Gurdyal S.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018865/
https://www.ncbi.nlm.nih.gov/pubmed/21155575
http://dx.doi.org/10.1021/jo102064p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018865/
https://www.ncbi.nlm.nih.gov/pubmed/21155575
http://dx.doi.org/10.1021/jo102064p

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