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Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

Obesity is a growing epidemic characterized by excess fat storage in adipocytes. Although lipoprotein receptors play important roles in lipid uptake, their role in controlling food intake and obesity is not known. Here we show that the lipoprotein receptor LRP1 regulates leptin signaling and energy...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Zhang, Juan, Zerbinatti, Celina, Zhan, Yan, Kolber, Benedict J., Herz, Joachim, Muglia, Louis J., Bu, Guojun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019112/
https://www.ncbi.nlm.nih.gov/pubmed/21264353
http://dx.doi.org/10.1371/journal.pbio.1000575