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Rrd1 isomerizes RNA polymerase II in response to rapamycin

BACKGROUND: In Saccharomyces cerevisiae, the immunosuppressant rapamycin engenders a profound modification in the transcriptional profile leading to growth arrest. Mutants devoid of Rrd1, a protein possessing in vitro peptidyl prolyl cis/trans isomerase activity, display striking resistance to the d...

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Detalles Bibliográficos
Autores principales: Jouvet, Nathalie, Poschmann, Jeremie, Douville, Julie, Bulet, Lisa, Ramotar, Dindial
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019149/
https://www.ncbi.nlm.nih.gov/pubmed/21129186
http://dx.doi.org/10.1186/1471-2199-11-92