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Novel Peptides Based on HIV-1 gp120 Sequence with Homology to Chemokines Inhibit HIV Infection in Cell Culture

The sequential interaction of the envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1) with CD4 and certain chemokine coreceptors initiates host cell entry of the virus. The appropriate chemokines have been shown to inhibit viral replication by blocking interaction of the gp120 e...

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Detalles Bibliográficos
Autores principales: Chertov, Oleg, Zhang, Ning, Chen, Xin, Oppenheim, Joost J., Lubkowski, Jacek, McGrath, Connor, Sowder, Raymond C., Crise, Bruce J., Malyguine, Anatoli, Kutzler, Michele A., Steele, Amber D., Henderson, Earl E., Rogers, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019152/
https://www.ncbi.nlm.nih.gov/pubmed/21264298
http://dx.doi.org/10.1371/journal.pone.0014474