The antagonism between MCT-1 and p53 affects the tumorigenic outcomes

BACKGROUND: MCT-1 oncoprotein accelerates p53 protein degradation via a proteosome pathway. Synergistic promotion of the xenograft tumorigenicity has been demonstrated in circumstance of p53 loss alongside MCT-1 overexpression. However, the molecular regulation between MCT-1 and p53 in tumor develop...

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Detalles Bibliográficos
Autores principales: Kasiappan, Ravi, Shih, Hung-Ju, Wu, Meng-Hsun, Choy, ChikOn, Lin, Tai-Du, Chen, Linyi, Hsu, Hsin-Ling
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019166/
https://www.ncbi.nlm.nih.gov/pubmed/21138557
http://dx.doi.org/10.1186/1476-4598-9-311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019166/
https://www.ncbi.nlm.nih.gov/pubmed/21138557
http://dx.doi.org/10.1186/1476-4598-9-311

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