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A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis

BACKGROUND: Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow the glycan to bind a variety of proteins, inclu...

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Detalles Bibliográficos
Autores principales: Yin, Xin, Truty, Jadwiga, Lawrence, Roger, Johns, Scott C, Srinivasan, R Sathish, Handel, Tracy M, Fuster, Mark M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019167/
https://www.ncbi.nlm.nih.gov/pubmed/21172016
http://dx.doi.org/10.1186/1476-4598-9-316