Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates

BACKGROUND: Ablation of TRPV1-expressing nociceptive fibers with the potent capsaicin analog resiniferatoxin (RTX) results in long lasting pain relief. RTX is particularly adaptable to focal application, and the induced chemical axonopathy leads to analgesia with a duration that is influenced by dos...

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Detalles Bibliográficos
Autores principales: Mitchell, Kendall, Bates, Brian D, Keller, Jason M, Lopez, Matthew, Scholl, Lindsey, Navarro, Julia, Madian, Nicholas, Haspel, Gal, Nemenov, Michael I, Iadarola, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019206/
https://www.ncbi.nlm.nih.gov/pubmed/21167052
http://dx.doi.org/10.1186/1744-8069-6-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019206/
https://www.ncbi.nlm.nih.gov/pubmed/21167052
http://dx.doi.org/10.1186/1744-8069-6-94

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