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Ribonucleotide reduction - horizontal transfer of a required function spans all three domains

BACKGROUND: Ribonucleotide reduction is the only de novo pathway for synthesis of deoxyribonucleotides, the building blocks of DNA. The reaction is catalysed by ribonucleotide reductases (RNRs), an ancient enzyme family comprised of three classes. Each class has distinct operational constraints, and...

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Detalles Bibliográficos
Autores principales: Lundin, Daniel, Gribaldo, Simonetta, Torrents, Eduard, Sjöberg, Britt-Marie, Poole, Anthony M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019208/
https://www.ncbi.nlm.nih.gov/pubmed/21143941
http://dx.doi.org/10.1186/1471-2148-10-383