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Striatal Pre- and Postsynaptic Profile of Adenosine A(2A) Receptor Antagonists

Striatal adenosine A(2A) receptors (A(2A)Rs) are highly expressed in medium spiny neurons (MSNs) of the indirect efferent pathway, where they heteromerize with dopamine D(2) receptors (D(2)Rs). A(2A)Rs are also localized presynaptically in cortico-striatal glutamatergic terminals contacting MSNs of...

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Detalles Bibliográficos
Autores principales: Orru, Marco, Bakešová, Jana, Brugarolas, Marc, Quiroz, César, Beaumont, Vahri, Goldberg, Steven R., Lluís, Carme, Cortés, Antoni, Franco, Rafael, Casadó, Vicent, Canela, Enric I., Ferré, Sergi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019225/
https://www.ncbi.nlm.nih.gov/pubmed/21264319
http://dx.doi.org/10.1371/journal.pone.0016088