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Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes

BACKGROUND: The orphan nuclear receptor TR4 (human testicular receptor 4 or NR2C2) plays a pivotal role in a variety of biological and metabolic processes. With no known ligand and few known target genes, the mode of TR4 function was unclear. RESULTS: We report the first genome-wide identification a...

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Detalles Bibliográficos
Autores principales: O'Geen, Henriette, Lin, Yu-Hsuan, Xu, Xiaoqin, Echipare, Lorigail, Komashko, Vitalina M, He, Daniel, Frietze, Seth, Tanabe, Osamu, Shi, Lihong, Sartor, Maureen A, Engel, James D, Farnham, Peggy J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019231/
https://www.ncbi.nlm.nih.gov/pubmed/21126370
http://dx.doi.org/10.1186/1471-2164-11-689