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Identifying a Transcription Factor’s Regulatory Targets from its Binding Targets
ChIP-chip data, which shows binding of transcription factors (TFs) to promoter regions in vivo, are widely used by biologists to identify the regulatory targets of TFs. However, the binding of a TF to a gene does not necessarily imply regulation. Thus, it is important to develop computational method...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020039/ https://www.ncbi.nlm.nih.gov/pubmed/21245946 http://dx.doi.org/10.4137/GRSB.S6458 |