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Epigenetic control of vascular smooth muscle cells in Marfan and non-Marfan thoracic aortic aneurysms

AIMS: Human thoracic aortic aneurysms (TAAs) are characterized by extracellular matrix breakdown associated with progressive smooth muscle cell (SMC) rarefaction. These features are present in all types of TAA: monogenic forms [mainly Marfan syndrome (MFS)], forms associated with bicuspid aortic val...

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Detalles Bibliográficos
Autores principales: Gomez, Delphine, Coyet, Aurélie, Ollivier, Véronique, Jeunemaitre, Xavier, Jondeau, Guillaume, Michel, Jean-Baptiste, Vranckx, Roger
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020128/
https://www.ncbi.nlm.nih.gov/pubmed/20829218
http://dx.doi.org/10.1093/cvr/cvq291