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Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

BACKGROUND: Ideally, disease modifying therapies for Alzheimer disease (AD) will be applied during the ‘preclinical’ stage (pathology present with cognition intact) before severe neuronal damage occurs, or upon recognizing very mild cognitive impairment. Developing and judiciously administering such...

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Detalles Bibliográficos
Autores principales: Perrin, Richard J., Craig-Schapiro, Rebecca, Malone, James P., Shah, Aarti R., Gilmore, Petra, Davis, Alan E., Roe, Catherine M., Peskind, Elaine R., Li, Ge, Galasko, Douglas R., Clark, Christopher M., Quinn, Joseph F., Kaye, Jeffrey A., Morris, John C., Holtzman, David M., Townsend, R. Reid, Fagan, Anne M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020224/
https://www.ncbi.nlm.nih.gov/pubmed/21264269
http://dx.doi.org/10.1371/journal.pone.0016032