Cargando…

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

BACKGROUND: Ideally, disease modifying therapies for Alzheimer disease (AD) will be applied during the ‘preclinical’ stage (pathology present with cognition intact) before severe neuronal damage occurs, or upon recognizing very mild cognitive impairment. Developing and judiciously administering such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perrin, Richard J., Craig-Schapiro, Rebecca, Malone, James P., Shah, Aarti R., Gilmore, Petra, Davis, Alan E., Roe, Catherine M., Peskind, Elaine R., Li, Ge, Galasko, Douglas R., Clark, Christopher M., Quinn, Joseph F., Kaye, Jeffrey A., Morris, John C., Holtzman, David M., Townsend, R. Reid, Fagan, Anne M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020224/ https://www.ncbi.nlm.nih.gov/pubmed/21264269 http://dx.doi.org/10.1371/journal.pone.0016032

Ejemplares similares

Quantitative Label-Free Proteomics for Discovery of Biomarkers in Cerebrospinal Fluid: Assessment of Technical and Inter-Individual Variation
por: Perrin, Richard J., et al.
Publicado: (2013)

SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease
por: Cruchaga, Carlos, et al.
Publicado: (2010)

Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease
por: Fagan, Anne M, et al.
Publicado: (2009)

Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor and Cognitive Function in Non-Demented Subjects
por: Li, Ge, et al.
Publicado: (2009)

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms
por: Wahrle, Suzanne E, et al.
Publicado: (2007)

Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults
por: Li, Ge, et al.
Publicado: (2017)

A Luminex Assay Detects Amyloid β Oligomers in Alzheimer’s Disease Cerebrospinal Fluid
por: Herskovits, Adrianna Z., et al.
Publicado: (2013)

Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: Their Role in Clinical Chemistry
por: Blennow, Kaj, et al.
Publicado: (2000)

Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer’s disease
por: Sutphen, Courtney L., et al.
Publicado: (2018)

Analysis of extracellular RNA in cerebrospinal fluid
por: Saugstad, Julie A., et al.
Publicado: (2017)

Predictive Modeling of Alzheimer’s and Parkinson’s Disease Using Metabolomic and Lipidomic Profiles from Cerebrospinal Fluid
por: Hwangbo, Nathan, et al.
Publicado: (2022)

Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males
por: Sandau, Ursula S., et al.
Publicado: (2022)

Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson’s Disease
por: Hossein-nezhad, Arash, et al.
Publicado: (2016)

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease
por: Kauwe, John S. K., et al.
Publicado: (2011)

Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects
por: Hata, Saori, et al.
Publicado: (2012)

Cerebrospinal Fluid MicroRNA Changes in Cognitively Normal Veterans With a History of Deployment-Associated Mild Traumatic Brain Injury
por: Lusardi, Theresa A., et al.
Publicado: (2021)

Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer’s disease in a memory clinic cohort
por: Kester, Maartje I., et al.
Publicado: (2015)

Tau oligomers in cerebrospinal fluid in Alzheimer's disease
por: Sengupta, Urmi, et al.
Publicado: (2017)

A cerebrospinal fluid microRNA signature as biomarker for glioblastoma
por: Akers, Johnny C., et al.
Publicado: (2017)

Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus
por: Limbrick, David D., et al.
Publicado: (2017)

Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer’s disease
por: Gangishetti, Umesh, et al.
Publicado: (2018)

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease
por: Twohig, Daniel, et al.
Publicado: (2018)

Postmortem Cerebrospinal Fluid Pleocytosis: A Marker of Inflammation or Postmortem Artifact?
por: Morris, James A., et al.
Publicado: (2012)

Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage
por: Meeker, Karin L., et al.
Publicado: (2022)

Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study
por: Leung, Yuk Yee, et al.
Publicado: (2015)

The cerebrospinal fluid in retinoblastoma.
por: Ifekwunigwe, A. E., et al.
Publicado: (1966)

Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease
por: Irwin, David J., et al.
Publicado: (2020)

Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
por: Johnson, Erik C. B., et al.
Publicado: (2023)

A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer’s disease
por: Budelier, Melissa M., et al.
Publicado: (2022)

Quantitative proteomics of delirium cerebrospinal fluid
por: Poljak, A, et al.
Publicado: (2014)

Altered Cerebrospinal Fluid (CSF) in Children with Ataxia Telangiectasia
por: Woelke, S., et al.
Publicado: (2020)

Cerebrospinal fluid homocysteine and hydrodynamics in chronic hydrocephalus
por: Schmidt, EA, et al.
Publicado: (2006)

Cerebrospinal Fluid Leak Masquerading as a Decubitus Ulcer in a Patient With Spina Bifida
por: Taylor, Erin M., et al.
Publicado: (2013)

THE CEREBROSPINAL FLUID IN SYPHILIS
por: Ellis, Arthur W. M., et al.
Publicado: (1913)

The concentration of desmethylmisonidazole in human tumours and in cerebrospinal fluid.
por: Dische, S., et al.
Publicado: (1981)

Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40
por: Deming, Yuetiva, et al.
Publicado: (2016)

Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis
por: Craig-Schapiro, Rebecca, et al.
Publicado: (2011)

Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function
por: Kundu, Payel, et al.
Publicado: (2022)

Entamoeba histolytica meningoencephalitis diagnosed by trophozoites in cerebrospinal fluid
por: Goh, L M L, et al.
Publicado: (2013)

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease
por: Llibre-Guerra, Jorge J., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7tmfokmgljfsf253icn3cbdgbj