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Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat

Hypertension is associated with heightened cardiac sympathetic drive whilst statins reduce angiotensin II (ATII) signalling, superoxide anion production and increase nitric oxide bioavailability, events that can potentially reduce peripheral cardiac sympathetic neurotransmission. We therefore invest...

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Detalles Bibliográficos
Autores principales: Herring, Neil, Lee, Chee Wan, Sunderland, Nicholas, Wright, Kathryn, Paterson, David J.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020274/
https://www.ncbi.nlm.nih.gov/pubmed/20933519
http://dx.doi.org/10.1016/j.yjmcc.2010.09.025