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The differential activity of interferon-α subtypes is consistent among distinct target genes and cell types

IFN-α proteins have been described to originate from 14 individual genes and allelic variants. However, the exceptional diversity of IFN-α and its functional impact are still poorly understood. To characterize the biological activity of IFN-α subtypes in relation to the cellular background, we inves...

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Detalles Bibliográficos
Autores principales: Moll, Herwig P., Maier, Thomas, Zommer, Anna, Lavoie, Thomas, Brostjan, Christine
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020287/
https://www.ncbi.nlm.nih.gov/pubmed/20943413
http://dx.doi.org/10.1016/j.cyto.2010.09.006