The use of the SAEM algorithm in MONOLIX software for estimation of population pharmacokinetic-pharmacodynamic-viral dynamics parameters of maraviroc in asymptomatic HIV subjects

Using simulated viral load data for a given maraviroc monotherapy study design, the feasibility of different algorithms to perform parameter estimation for a pharmacokinetic-pharmacodynamic-viral dynamics (PKPD-VD) model was assessed. The assessed algorithms are the first-order conditional estimatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Phylinda L. S., Jacqmin, Philippe, Lavielle, Marc, McFadyen, Lynn, Weatherley, Barry
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020311/
https://www.ncbi.nlm.nih.gov/pubmed/21088872
http://dx.doi.org/10.1007/s10928-010-9175-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020311/
https://www.ncbi.nlm.nih.gov/pubmed/21088872
http://dx.doi.org/10.1007/s10928-010-9175-z

Ejemplares similares