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Molecular Basis for Vulnerability to Mitochondrial and Oxidative Stress in a Neuroendocrine CRI-G1 Cell Line

BACKGROUND: Many age-associated disorders (including diabetes, cancer, and neurodegenerative diseases) are linked to mitochondrial dysfunction, which leads to impaired cellular bioenergetics and increased oxidative stress. However, it is not known what genetic and molecular pathways underlie differe...

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Detalles Bibliográficos
Autores principales: Chandiramani, Natasha, Wang, Xianhong, Margeta, Marta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020905/
https://www.ncbi.nlm.nih.gov/pubmed/21249230
http://dx.doi.org/10.1371/journal.pone.0014485