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Telomeric recombination induced by dysfunctional telomeres

 Telomere maintenance is essential for cellular immortality, and most cancer cells maintain their telomeres through the enzyme telomerase. Telomeres and telomerase represent promising anticancer targets. However, 15% of cancer cells maintain their telomeres through alternative recombination-based me...

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Detalles Bibliográficos
Autores principales: Brault, Marie Eve, Autexier, Chantal
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020914/
https://www.ncbi.nlm.nih.gov/pubmed/21118998
http://dx.doi.org/10.1091/mbc.E10-02-0173