Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

Nemo-like kinase (NLK) is an evolutionarily conserved protein kinase that phosphorylates several transcription factors. However, the molecular mechanisms that regulate NLK activity have been poorly understood. Here we show that homodimerization of NLK is required for its activation and nuclear local...

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Detalles Bibliográficos
Autores principales: Ishitani, Shizuka, Inaba, Kenji, Matsumoto, Kunihiro, Ishitani, Tohru
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020921/
https://www.ncbi.nlm.nih.gov/pubmed/21118996
http://dx.doi.org/10.1091/mbc.E10-07-0605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020921/
https://www.ncbi.nlm.nih.gov/pubmed/21118996
http://dx.doi.org/10.1091/mbc.E10-07-0605

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