Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion

Loss of retinoblastoma (Rb) tumor suppressor function is associated with human malignancies. Molecular and genetic mechanisms responsible for tumorigenic Rb downregulation are not fully defined. Through a forward genetic screen and positional cloning, we identified and characterized a zebrafish ubiq...

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Detalles Bibliográficos
Autores principales: Ríos, Yesenia, Melmed, Shlomo, Lin, Shuo, Liu, Ning-Ai
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020934/
https://www.ncbi.nlm.nih.gov/pubmed/21249182
http://dx.doi.org/10.1371/journal.pgen.1001271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020934/
https://www.ncbi.nlm.nih.gov/pubmed/21249182
http://dx.doi.org/10.1371/journal.pgen.1001271

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