Taking Multiple Infections of Cells and Recombination into Account Leads to Small Within-Host Effective-Population-Size Estimates of HIV-1

Whether HIV-1 evolution in infected individuals is dominated by deterministic or stochastic effects remains unclear because current estimates of the effective population size of HIV-1 in vivo, N(e), are widely varying. Models assuming HIV-1 evolution to be neutral estimate N(e)∼10(2)–10(4), smaller...

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Detalles Bibliográficos
Autores principales: Balagam, Rajesh, Singh, Vasantika, Sagi, Aparna Raju, Dixit, Narendra M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020941/
https://www.ncbi.nlm.nih.gov/pubmed/21249189
http://dx.doi.org/10.1371/journal.pone.0014531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020941/
https://www.ncbi.nlm.nih.gov/pubmed/21249189
http://dx.doi.org/10.1371/journal.pone.0014531

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