Creatine Transporter (CrT; Slc6a8) Knockout Mice as a Model of Human CrT Deficiency

Mutations in the creatine (Cr) transporter (CrT; Slc6a8) gene lead to absence of brain Cr and intellectual disabilities, loss of speech, and behavioral abnormalities. To date, no mouse model of CrT deficiency exists in which to understand and develop treatments for this condition. The purpose of thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Skelton, Matthew R., Schaefer, Tori L., Graham, Devon L., deGrauw, Ton J., Clark, Joseph F., Williams, Michael T., Vorhees, Charles V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020968/
https://www.ncbi.nlm.nih.gov/pubmed/21249153
http://dx.doi.org/10.1371/journal.pone.0016187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020968/
https://www.ncbi.nlm.nih.gov/pubmed/21249153
http://dx.doi.org/10.1371/journal.pone.0016187

Ejemplares similares