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Creatine Transporter (CrT; Slc6a8) Knockout Mice as a Model of Human CrT Deficiency
Mutations in the creatine (Cr) transporter (CrT; Slc6a8) gene lead to absence of brain Cr and intellectual disabilities, loss of speech, and behavioral abnormalities. To date, no mouse model of CrT deficiency exists in which to understand and develop treatments for this condition. The purpose of thi...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020968/ https://www.ncbi.nlm.nih.gov/pubmed/21249153 http://dx.doi.org/10.1371/journal.pone.0016187 |