A functional alternative splicing mutation in human tryptophan hydroxylase-2

The brain serotonergic system has an essential role in the physiological functions of the central nervous system and dysregulation of serotonin (5-HT) homeostasis has been implicated in many neuropsychiatric disorders. The tryptophan hydroxylase-2 (TPH2) gene is the rate-limiting enzyme in brain 5-H...

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Detalles Bibliográficos
Autores principales: Zhang, X, Nicholls, P J, Laje, G, Sotnikova, T D, Gainetdinov, R R, Albert, P R, Rajkowska, G, Stockmeier, C A, Speer, M C, Steffens, D C, Austin, M C, McMahon, F J, Krishnan, K R R, Garcia-Blanco, M A, Caron, M G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021090/
https://www.ncbi.nlm.nih.gov/pubmed/20856248
http://dx.doi.org/10.1038/mp.2010.99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021090/
https://www.ncbi.nlm.nih.gov/pubmed/20856248
http://dx.doi.org/10.1038/mp.2010.99

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