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R1467H Variants of Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) are Associated with Type 2 Diabetes Mellitus in Koreans

BACKGROUND: The human Rho guanine nucleotide exchange factor 11 (ARHGEF11) functions as an activator of Rho GTPases and is thought to influence insulin signaling. The R1467H variant of ARHGEF11 has been reported to be associated with susceptibility to type 2 diabetes mellitus (T2DM) in Western popul...

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Detalles Bibliográficos
Autores principales: Jin, Qing Song, Kim, So Hun, Piao, Shan-Ji, Lim, Hyun Ae, Lee, Seung Youn, Hong, Seong Bin, Kim, Yong Seong, Lee, Hun-Jae, Nam, Moonsuk
Formato: Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021113/
https://www.ncbi.nlm.nih.gov/pubmed/21246010
http://dx.doi.org/10.4093/kdj.2010.34.6.368