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Functional Characterization of Aquaporin-4 Specific T Cells: Towards a Model for Neuromyelitis Optica
BACKGROUND: Antibodies to the water channel protein aquaporin-4 (AQP4), which is expressed in astrocytic endfeet at the blood brain barrier, have been identified in the serum of Neuromyelitis optica (NMO) patients and are believed to induce damage to astrocytes. However, AQP4 specific T helper cell...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021520/ https://www.ncbi.nlm.nih.gov/pubmed/21264240 http://dx.doi.org/10.1371/journal.pone.0016083 |