Functional Characterization of Aquaporin-4 Specific T Cells: Towards a Model for Neuromyelitis Optica

BACKGROUND: Antibodies to the water channel protein aquaporin-4 (AQP4), which is expressed in astrocytic endfeet at the blood brain barrier, have been identified in the serum of Neuromyelitis optica (NMO) patients and are believed to induce damage to astrocytes. However, AQP4 specific T helper cell...

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Detalles Bibliográficos
Autores principales: Kalluri, Sudhakar Reddy, Rothhammer, Veit, Staszewski, Ori, Srivastava, Rajneesh, Petermann, Franziska, Prinz, Marco, Hemmer, Bernhard, Korn, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021520/
https://www.ncbi.nlm.nih.gov/pubmed/21264240
http://dx.doi.org/10.1371/journal.pone.0016083

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