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Species Difference of CD137 Ligand Signaling in Human and Murine Monocytes

BACKGROUND: Stimulation of CD137 ligand on human monocytes has been shown to induce DC differentiation, and these CD137L-DCs are more potent than classical DCs, in stimulating T cell responses in vitro. To allow an in vivo evaluation of the potency of CD137L-DCs in murine models we aimed at generati...

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Detalles Bibliográficos
Autores principales: Tang, Qianqiao, Jiang, Dongsheng, Shao, Zhe, Martínez Gómez, Julia M., Schwarz, Herbert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021528/
https://www.ncbi.nlm.nih.gov/pubmed/21264248
http://dx.doi.org/10.1371/journal.pone.0016129