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Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani

In this report, we demonstrate the existence of the ubiquitin fold modifier-1 (Ufm1) and its conjugation pathway in trypanosomatid parasite Leishmania donovani. LdUfm1 is activated by E1-like enzyme LdUba5. LdUfc1 (E2) specifically interacted with LdUfm1 and LdUba5 to conjugate LdUfm1 to proteinaceo...

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Detalles Bibliográficos
Autores principales: Gannavaram, Sreenivas, Sharma, Paresh, Duncan, Robert C., Salotra, Poonam, Nakhasi, Hira L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021533/
https://www.ncbi.nlm.nih.gov/pubmed/21264253
http://dx.doi.org/10.1371/journal.pone.0016156