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Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity

In our studies of ovarian cancer cells we have identified subpopulations of cells that are in a transitory E/M hybrid stage, i.e. cells that simultaneously express epithelial and mesenchymal markers. E/M cells are not homogenous but, in vitro and in vivo, contain subsets that can be distinguished ba...

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Detalles Bibliográficos
Autores principales: Strauss, Robert, Li, Zong-Yi, Liu, Ying, Beyer, Ines, Persson, Jonas, Sova, Pavel, Möller, Thomas, Pesonen, Sari, Hemminki, Akseli, Hamerlik, Petra, Drescher, Charles, Urban, Nicole, Bartek, Jiri, Lieber, André
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021543/
https://www.ncbi.nlm.nih.gov/pubmed/21264259
http://dx.doi.org/10.1371/journal.pone.0016186