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Intra-arterial tert-Butyl-Hydroperoxide Infusion Induces an Exacerbated Sensory Response in the Rat Hind Limb and is Associated with an Impaired Tissue Oxygen Uptake

The objective of this study was to investigate oxidative stress and oxygen extraction mechanisms in an animal model of continuous intra-arterial infusion of a free radical donor and in an in vitro model using isolated mitochondria. tert-Butyl-hydroperoxide (tert-BuOOH, 25 mM) was infused for 24 h in...

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Detalles Bibliográficos
Autores principales: Tan, Edward C. T. H., van Goor, Harry, Bahrami, Soheyl, Kozlov, Andrey V., Leixnering, Martin, Redl, Heinz, Goris, R. Jan A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021700/
https://www.ncbi.nlm.nih.gov/pubmed/20386971
http://dx.doi.org/10.1007/s10753-010-9207-2